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En los estudios clínicos realizados en diabéticos, tirzepatida ha demostrado, concretamente, un control glucémico (hasta el 87% de los pacientes alcanzó niveles de hemoglobina glicada (HbA1c) de 6,5% o inferiores en comparación con el 66,2% de los tratados con semaglutida 1mg), e incluso alrededor del 50% alcanza niveles similares a los de una persona sin diabetes (HbA1c =5,7%) frente al 19,7% que lo consigue con semaglutida, con pérdidas de peso de media de hasta 12,4kg con tirzepatida frente a 6,2kg con semaglutida, todo ello con un perfil de seguridad favorable

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These often lessen over time but can affect treatment persistence